Professor Patrick Gunning

University of Toronto Mississauga

Patrick Gunning Outlines his Quest to Find New Cancer Treatments by Developing Small Molecule STAT Inhibitors

Professor Patrick Gunning discusses his work developing small molecule inhibitors for STAT proteins, with the aim of developing new cancer treatments. STAT-3 is found to be hyperactive in over 70% of human cancer, leading to uncontrolled cell growth, whilst STAT-5 has recently been identified as a target in haematological oncology.

This video won the Drug Discovery & Development Video Interview of the Year in the 2018 Scientists' Choice Awards. Find out more about the awards here



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Professor Patrick Gunning
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Professor Patrick Gunning

Biography

Patrick Gunning is full professor and Canada Research Chair in Medicinal Chemistry at University of Toronto. More
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Professor Patrick Gunning

University of Toronto Mississauga

Patrick Gunning is full professor and Canada Research Chair in Medicinal Chemistry at University of Toronto. In 2007, Patrick accepted an Assistant Professorship position at the University of Toronto Mississauga Chemistry Department. In the last eight years he has developed a dynamic and diverse medicinal chemistry program targeting protein-protein interactions, a most challenging of targets. Moreover, Patrick’s team develop inhibitors of proteins that drive the most rare and lethal of human cancers, including glioblastoma, acute myeloid leukemia, multiple myeloma, and refractory medullablastoma.